HyperFlux - Metabolic flux analysis to determine the effects of muscle hypertrophy and atrophy on metabolic health

Metabolomics serves as a sophisticated analytical tool to discern subtle alterations in the body's metabolic profile, providing an intricate assessment of its overall physiological state. The overarching goal of the HyperMet research unit is to investigate how muscle hypertrophy and atrophy impact metabolic health, influencing adipose tissue, glucose regulation, and bone and tumor metabolism. This service project is dedicated to providing support for stable-isotope-based metabolic flux analysis in both in vitro and in vivo systems. The objectives include providing comprehensive [13C] Metabolic Flux Analysis (MFA) support for in vitro settings, extending MFA support to in vivo systems, and offering tailored training to the consortium to enhance proficiency in conducting metabolic flux experiments.