HyperCancer - Investigating the metabolic consequences of muscle-tumour interplay

Cancer is increasingly understood as a systemic metabolic disease, given its ability to impair energy homeostasis and induce skeletal muscle atrophy. These impacts are strongly associated with a worsened disease prognosis. Metabolic dysfunction and tissue wasting in cancer are summarized under the term cancer cachexia. With HyperCancer, we aim to apply advanced methods of metabolic research to elucidate the metabolic landscape of cancer-muscle interaction in cachexia in relation to muscle atrophy and hypertrophy.