Nature Immunology Journal, December 2024: Efficacy of CTLA-4 checkpoint therapy is dependent on IL-21 signaling to mediate cytotoxic reprogramming of PD-1+CD8+ T cells
Congratulations to Prof. Dr. Dr. Bertram Bengsch and his team from the University Hospital Freiburg on their publication in the Nature Immunology Journal. Zhang et al. describe the dependence of IL-21 signaling on the efficacy of CTLA4 checkpoint therapy in melanoma.
https://www.nature.com/articles/s41590-024-02027-0
Molecular Metabolism Journal, September 2024: Metabolic profiling of single cells by exploiting NADH and FAD fluorescence via flow cytometry
Congratulations to Prof. Dr. Dirk Mielenz and his team from FAU in Erlangen. In their publication, Abir et al. describe a label-free method to detect metabolic changes by analyzing the redox ratio of FAD/NADH fluorescence in real time in viable cell populations using flow cytometry.
Blood Cancer Journal, August 2024: B cell intrinsic RANK signaling cooperates with TCL1 to induce lineage-dependent B cell transformation
We congratulate PD Dr. Maike Buchner and her team at the Technical University of Munich on their latest publication in the Blood Cancer Journal. In their study, Pfeuffer et al. show interesting data on the influence of RANK signaling on B cell transformation and the tumor microenvironment.