In order to research the interaction of B cell metabolism and signaling, specialists in the field of immunology from Munich, Erlangen, Freiburg and Berlin have joined forces as part of the DFG research group FOR5560. In seven research projects, the scientists are investigating various aspects of B cell biology, B cell metabolism and B cell signal transduction in the context of autoimmune and malignant diseases. By merging the projects, new collaborations will be created, resources and expertise will be optimally utilized and new approaches for the therapy of B cell diseases will be found.